Closed Studies
Closed Interventional Studies | Closed Observational Studies
List of Closed Interventional Studies
This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients.
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The purpose of this study is to assess the safety and efficacy of PRA023 in participants with moderately to severely active Ulcerative Colitis.
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This phase 2 clinical trial will evaluate the safety and immunogenicity of additional doses of prototype and variant vaccine candidates in previously vaccinated participants with or without prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and will evaluate innate, cellular, and humoral immune responses to inform on how to shift the immune response to…
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The primary aim of this study is to determine if reducing exposure to dietary oxysterols with a plant-based, oxysterol-free diet that follows American Diabetes Association (ADA) guidelines (PB-ADAØ) will improve β-cell function and glycemic control among AAs with prediabetes and early diabetes (HbA1c 5.7% – 7.0%) when compared to the standard ADA (SADA) diet with…
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The purpose of this study is to evaluate the clinical efficacy, clinical and endoscopic efficacy and safety of guselkumab in participants with Crohn’s disease.
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This is a research study of an investigational vaccine made by Novavax, Inc. called “SARS-CoV-2 rS with Matrix-M1™ Adjuvant”. The study is a multicenter, global study with countries selected based on the expected COVID-19 epidemiology and healthcare system characteristics. The objectives are to determine whether the vaccine prevents COVID-19 disease, to see if the study…
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The purpose of this study is to assess the effect of sacubitril/valsartan vs. valsartan on changes in NT-proBNP, safety, and tolerability in HFpEF patients with a WHF event (HFpEF decompensation) who have been stabilized and initiated at the time of or within 30 days post-decompensation.
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ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants to enable the monitoring of possible delayed effects of aspirin treatment, primarily on cancer incidence, metastases and mortality.
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The purpose of this study is to evaluate whether certain genetic factors predispose some smokers to develop COPD more than others.
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Goal is to identify solutions to lower the effects of serious illness in pregnancy and/or after delivery which can sometimes lead to death and to advocate for changes in laws and programs to prevent future maternal deaths and severe illness.
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The purpose of this study is to determine if body weight and inflammation influence the concentration of antibodies made in response to the COVID-19 vaccine.
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The Morehouse School of Medicine Prevention Research Center conducted a Community Health needs and Assets Assessment. As a neighborhood resident of Neighborhood Planning, your opinion about the health concerns and resources in your community is important to us. The information we received from the survey help us develop health programs and improve prevention education services…
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A prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
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