Active Studies
Active Interventional Studies | Active Observational Studies
List of Active Interventional Studies
The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical meaningful motor progression over 78 weeks in subjects with Parkinson’s disease who have a pathogenic variant in the glucocerebrosidase 1 (GBA1) gene (GBA-PD).
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The ACTIV-6 research study is testing several medications that are already approved for other diseases to see if they can help people with mild to moderate COVID-19 feel better.
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A Phase 2/3 Adaptive, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VX-147 in Subjects Aged 12 Years and Older With APOL1-mediated Proteinuric Kidney Disease. The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of VX-147 in participants aged 12 years and older with apolipoprotein L1 (APOL1)-mediated proteinuric…
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A randomized double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) in US Black/African American & Hispanic patient populations with elevated Lp(a) and established atherosclerotic cardiovascular disease.
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This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn’s disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics).
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The primary aim of this study is to determine if reducing exposure to dietary oxysterols with a plant-based, oxysterol-free diet that follows American Diabetes Association (ADA) guidelines (PB-ADAØ) will improve β-cell function and glycemic control among AAs with prediabetes and early diabetes (HbA1c 5.7% – 7.0%) when compared to the standard ADA (SADA) diet with…
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A Phase III, Multicenter, Cross-Over Comparative Study to Evaluate the Effectiveness of the Rover Cervex-Brush (Cervix-Examination Brush) device vs. the Personal Pap Smear (TM) Device for Collection of Cervical Cells within a Cytological Sample for Detecting Cervical Dysplasia or Neoplasia
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Overview Morehouse School of Medicine is participating in a new clinical trial called the HUMMINGBIRD study, a Phase 2/3 study to evaluate the safety and immunogenicity of an investigational vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 in pediatric participants. Is it free to participate in a study? There will be…
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A Phase 3 trial to evaluate the BP-lowering effect of lorundrostat in participants with uncontrolled and resistant hypertension taking between 2 and 5 anti-hypertensive medications.
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Study to determine the effect of a one month prescribed, eucaloric low fat diet (LFD) on daily urinary reproductive hormone excretion.
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This project will utilize telehealth monitoring, wearable devices and smartphone applications to describe the autonomic characteristics associated with persistent symptoms of patients with recent COVID-19 infection.
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This is a study to learn if a study medicine can help prevent Respiratory Syncytial Virus (RSV) infection in babies who are more likely to get severe RSV illness.
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A Doubleblind, Randomized, Placebocontrolled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a) – Amgen 20180096 The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease death (CHD death),…
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This study seeks to explore if a plant-based diet and exercise routine will assist African American women breast or endometrial cancer survivors in preventing recurrence.
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Increasingly, over the last 15 years, antibiotic resistant infections in the Atlanta 20 county metropolitan area have continued to soar — this area represents a diverse racial/ethnic population. Project HIRaCAARI stands for Project Health Information Resources and Community-Associated Antibiotic Resistant Infections. The goal of Project HIRaCAARI is to reduce health disparities among people of color…
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The All of Us Research Program aims to speed up health research and medical breakthroughs by collecting data from one million people. Precision medicine, which takes into account an individual’s unique factors, is the goal of the program. This Program seeks to engage at least one million diverse participants to advance precision medicine and improve…
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ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants to enable the monitoring of possible delayed effects of aspirin treatment, primarily on cancer incidence, metastases and mortality.
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This project tests an intervention—a communication tool plus clinician training in its use—designed to improve communication about prognosis and support clinicians and families of older adults with serious traumatic injury in the ICU.
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The purpose of this study is to evaluate whether certain genetic factors predispose some smokers to develop COPD more than others.
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In this study you will first be asked to participate in a one-on-one interview (Phase 1). You will then be asked to complete regular surveys over three months (Phase 2). If you decide to participate in this study you will be compensated for your time.
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This study is designed to understand the role of D. hansenii in the most severe form of Crohn’s disease (CD) – peri-anal and fistulizing disease in patients undergoing routine clinical care colonoscopy.
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The purpose of this study is to determine if body weight and inflammation influence the concentration of antibodies made in response to the COVID-19 vaccine.
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The purpose of this study is to develop a central repository for PD-related genomic data by individuals who consent to deposit their data and bank their residual DNA obtained through clinical genetic testing for future research use.
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A multi-center observational study of NCTH patients being treated with the pREBOA-PRO™ catheter for partial or complete occlusion as standard of care. Detailed prospective clinical data will be collected to identify outcomes and complications post treatment of non-compressible torso hemorrhage (NCTH)
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The purpose of this study is to look at racial disparities in people with Parkinson’s Disease (PD) by studying symptoms and signs, management, and genes in Black PD patients compared to a group of White PD patients.
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A Multi-site Observational Study of Post-Acute Sequalae of SARS-CoV-2 RECOVER is a research project that aims to learn about the long-term health effects of COVID. To understand COVID, we need to include many people in RECOVER studies. You can participate whether you have COVID now, had COVID before, or never had COVID. We need to…
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RECOVER is a research project that aims to learn about the long-term health effects of COVID. To understand COVID, we need to include many people in RECOVER studies. You can participate whether you have COVID now, had COVID before, or never had COVID. We need to learn how COVID affects all people, and that means…
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This study aims to develop blood tests that can provide accurate, convenient and patient-friendly options for cancer screening.
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