List of Active Interventional Studies

ACTIV-6

The ACTIV-6 research study is testing several medications that are already approved for other diseases to see if they can help people with mild to moderate COVID-19 feel better.

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Amplitude (VERTEX)

The AMPLITUDE clinical research study is exploring an investigational study drug for APOL1-mediated kidney disease—a type of chronic kidney disease that occurs in people of African ancestry. Here you can find more information about chronic kidney disease and APOL1-mediated kidney disease, genetic testing and the AMPLITUDE clinical research study for patients, families, caregivers, and communities.

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AMPLITUDE (VERTEX 301)

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of VX-147 in participants aged 12 years and older with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease.

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CULTIVATE

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn’s disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics).

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HUMMINGBIRD Pediatric COVID-19 Vaccine Study

Overview Morehouse School of Medicine is participating in a new clinical trial called the HUMMINGBIRD study, a Phase 2/3 study to evaluate the safety and immunogenicity of an investigational vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 in pediatric participants. Is it free to participate in a study? There will be…

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Long Haulers

This project will utilize telehealth monitoring, wearable devices and smartphone applications to describe the autonomic characteristics associated with persistent symptoms of patients with recent COVID-19 infection.

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Lullaby

The purpose of this study is to assess immune response and safety of various potencies of an investigational chickenpox vaccine given to healthy children 12 to 15 months of age.

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Merck RSV

This is a study to learn if a study medicine can help prevent Respiratory Syncytial Virus (RSV) infection in babies who are more likely to get severe RSV illness.

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OCEAN(a)-Outcomes

The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants with atherosclerotic cardiovascular disease (ASCVD) and elevated Lipoprotein(a).

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Plant-based Diet and Exercise

This study seeks to explore if a plant-based diet and exercise routine will assist African American women breast or endometrial cancer survivors in preventing recurrence.

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Project HIRaCAARI

Increasingly, over the last 15 years, antibiotic resistant infections in the Atlanta 20 county metropolitan area have continued to soar — this area represents a diverse racial/ethnic population. Project HIRaCAARI stands for Project Health Information Resources and Community-Associated Antibiotic Resistant Infections. The goal of Project HIRaCAARI is to reduce health disparities among people of color…

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List of Active Observational Studies

All of Us

The All of Us Research Program aims to speed up health research and medical breakthroughs by collecting data from one million people. Precision medicine, which takes into account an individual’s unique factors, is the goal of the program. This Program seeks to engage at least one million diverse participants to advance precision medicine and improve…

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ASCVD (Amgen 20210057)

The purpose of this study is to characterize the distribution of lipoprotein(a) (Lp(a)) levels among participants with a history of ASCVD as defined by their medical history.

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Best Case/Worst Case Communication

This project tests an intervention—a communication tool plus clinician training in its use—designed to improve communication about prognosis and support clinicians and families of older adults with serious traumatic injury in the ICU.

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EMA in Heart Failure

In this study you will first be asked to participate in a one-on-one interview (Phase 1). You will then be asked to complete regular surveys over three months (Phase 2). If you decide to participate in this study you will be compensated for your time.

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FISTULA

This study is designed to understand the role of D. hansenii in the most severe form of Crohn’s disease (CD) – peri-anal and fistulizing disease in patients undergoing routine clinical care colonoscopy.

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PDGENeration

The purpose of this study is to develop a central repository for PD-related genomic data by individuals who consent to deposit their data and bank their residual DNA obtained through clinical genetic testing for future research use.

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RECOVER

RECOVER is a research project that aims to learn about the long-term health effects of COVID. To understand COVID, we need to include many people in RECOVER studies. You can participate whether you have COVID now, had COVID before, or never had COVID. We need to learn how COVID affects all people, and that means…

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VALLANIA

This study aims to develop blood tests that can provide accurate, convenient and patient-friendly options for cancer screening.

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