List of Active Interventional Studies

LIBRA

A 52-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group, group sequential, Phase 3 study to evaluate the efficacy and safety of rilzabrutinib in patients aged 10 to 65 years with sickle-cell disease (LIBRA)

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Collegiate Athletes Study

A cross-sectional study will be done with Black collegiate runners in Atlanta, GA. Members of the men’s and women’s varsity cross-country teams at Clark Atlanta University will be asked to participate in this IRB approved study.

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Dietary Oxysterol

The primary aim of this study is to determine if reducing exposure to dietary oxysterols with a plant-based, oxysterol-free diet that follows American Diabetes Association (ADA) guidelines (PB-ADAØ) will improve β-cell function and glycemic control among AAs with prediabetes and early diabetes (HbA1c 5.7% – 7.0%) when compared to the standard ADA (SADA) diet with…

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HUMMINGBIRD Pediatric COVID-19 Vaccine Study

Overview Morehouse School of Medicine is participating in a new clinical trial called the HUMMINGBIRD study, a Phase 2/3 study to evaluate the safety and immunogenicity of an investigational vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 in pediatric participants. Is it free to participate in a study? There will be…

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LFD-Dietary Reversal

Study to determine the effect of a one month prescribed, eucaloric low fat diet (LFD) on daily urinary reproductive hormone excretion.

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OCEAN(a)-Outcomes

A Doubleblind, Randomized, Placebocontrolled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a) – Amgen 20180096 The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease death (CHD death),…

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PEARL

This study will evaluate the safety and immune response of a new candidate RSV vaccine in infants and toddlers.

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RECOVER – Autonomic

RECOVER-AUTONOMIC is focused on autonomic dysfunction symptoms related to Long COVID, such as fast heart rate, dizziness, and fatigue. These symptoms are related to damage to nerves that are part of the autonomic nervous system, which controls automatic body functions like heartbeat and blood pressure. RECOVER-AUTONOMIC is studying possible treatments for adults who have an autonomic…

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RECOVER Vital

RECOVER-VITAL is focused on viral persistence, which is when the virus that causes COVID-19 stays in the body and causes damage to organs or the immune system (the body’s system that fights off illnesses) to not function properly. Researchers think that viral persistence may lead to Long COVID symptoms.

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List of Active Observational Studies

All of Us

The All of Us Research Program aims to speed up health research and medical breakthroughs by collecting data from one million people. Precision medicine, which takes into account an individual’s unique factors, is the goal of the program. This Program seeks to engage at least one million diverse participants to advance precision medicine and improve…

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Best Case/Worst Case Communication

This project tests an intervention—a communication tool plus clinician training in its use—designed to improve communication about prognosis and support clinicians and families of older adults with serious traumatic injury in the ICU.

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EMA in Heart Failure

In this study you will first be asked to participate in a one-on-one interview (Phase 1). You will then be asked to complete regular surveys over three months (Phase 2). If you decide to participate in this study you will be compensated for your time.

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Obesity

The purpose of this study is to determine if body weight and inflammation influence the concentration of antibodies made in response to the COVID-19 vaccine.

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PROMPT Study

A multi-center observational study of NCTH patients being treated with the pREBOA-PRO™ catheter for partial or complete occlusion as standard of care. Detailed prospective clinical data will be collected to identify outcomes and complications post treatment of non-compressible torso hemorrhage (NCTH)

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RECOVER Adult

A Multi-site Observational Study of Post-Acute Sequalae of SARS-CoV-2 RECOVER is a research project that aims to learn about the long-term health effects of COVID. To understand COVID, we need to include many people in RECOVER studies. You can participate whether you have COVID now, had COVID before, or never had COVID. We need to…

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VALLANIA

This study aims to develop blood tests that can provide accurate, convenient and patient-friendly options for cancer screening.

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