List of Closed Interventional Studies

ACTIV-4

This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients.

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ARTEMIS

The purpose of this study is to assess the safety and efficacy of PRA023 in participants with moderately to severely active Ulcerative Colitis.

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COVAIL

This phase 2 clinical trial will evaluate the safety and immunogenicity of additional doses of prototype and variant vaccine candidates in previously vaccinated participants with or without prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and will evaluate innate, cellular, and humoral immune responses to inform on how to shift the immune response to…

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CULTIVATE

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn’s disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics).

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GALAXI

The purpose of this study is to evaluate the clinical efficacy, clinical and endoscopic efficacy and safety of guselkumab in participants with Crohn’s disease.

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Lullaby

The purpose of this study is to assess immune response and safety of various potencies of an investigational chickenpox vaccine given to healthy children 12 to 15 months of age.

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Novavax

This is a research study of an investigational vaccine made by Novavax, Inc. called “SARS-CoV-2 rS with Matrix-M1™ Adjuvant”. The study is a multicenter, global study with countries selected based on the expected COVID-19 epidemiology and healthcare system characteristics. The objectives are to determine whether the vaccine prevents COVID-19 disease, to see if the study…

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PARAGLIDE

The purpose of this study is to assess the effect of sacubitril/valsartan vs. valsartan on changes in NT-proBNP, safety, and tolerability in HFpEF patients with a WHF event (HFpEF decompensation) who have been stabilized and initiated at the time of or within 30 days post-decompensation.

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Project HIRaCAARI

Increasingly, over the last 15 years, antibiotic resistant infections in the Atlanta 20 county metropolitan area have continued to soar — this area represents a diverse racial/ethnic population. Project HIRaCAARI stands for Project Health Information Resources and Community-Associated Antibiotic Resistant Infections. The goal of Project HIRaCAARI is to reduce health disparities among people of color…

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List of Closed Observational Studies

ASCVD (Amgen 20210057)

The purpose of this study is to characterize the distribution of lipoprotein(a) (Lp(a)) levels among participants with a history of ASCVD as defined by their medical history.

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GA IMPROVE

Goal is to identify solutions to lower the effects of serious illness in pregnancy and/or after delivery which can sometimes lead to death and to advocate for changes in laws and programs to prevent future maternal deaths and severe illness.

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PRC Community Assessment

The Morehouse School of Medicine Prevention Research Center conducted a Community Health needs and Assets Assessment. As a neighborhood resident of Neighborhood Planning, your opinion about the health concerns and resources in your community is important to us. The information we received from the survey help us develop health programs and improve prevention education services…

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PREMEPT CRC

A prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.

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Example Study

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