Closed Studies
Closed Interventional Studies | Closed Observational Studies
List of Closed Interventional Studies
The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical meaningful motor progression over 78 weeks in subjects with Parkinson’s disease who have a pathogenic variant in the glucocerebrosidase 1 (GBA1) gene (GBA-PD).
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This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients.
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The ACTIV-6 research study is testing several medications that are already approved for other diseases to see if they can help people with mild to moderate COVID-19 feel better.
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The purpose of this study is to assess the safety and efficacy of PRA023 in participants with moderately to severely active Ulcerative Colitis.
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This phase 2 clinical trial will evaluate the safety and immunogenicity of additional doses of prototype and variant vaccine candidates in previously vaccinated participants with or without prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and will evaluate innate, cellular, and humoral immune responses to inform on how to shift the immune response to…
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A randomized double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) in US Black/African American & Hispanic patient populations with elevated Lp(a) and established atherosclerotic cardiovascular disease.
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This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn’s disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics).
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The purpose of this study is to evaluate the clinical efficacy, clinical and endoscopic efficacy and safety of guselkumab in participants with Crohn’s disease.
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A Phase 3 trial to evaluate the BP-lowering effect of lorundrostat in participants with uncontrolled and resistant hypertension taking between 2 and 5 anti-hypertensive medications.
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This project will utilize telehealth monitoring, wearable devices and smartphone applications to describe the autonomic characteristics associated with persistent symptoms of patients with recent COVID-19 infection.
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The purpose of this study is to assess immune response and safety of various potencies of an investigational chickenpox vaccine given to healthy children 12 to 15 months of age.
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This is a study to learn if a study medicine can help prevent Respiratory Syncytial Virus (RSV) infection in babies who are more likely to get severe RSV illness.
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This is a research study of an investigational vaccine made by Novavax, Inc. called “SARS-CoV-2 rS with Matrix-M1™ Adjuvant”. The study is a multicenter, global study with countries selected based on the expected COVID-19 epidemiology and healthcare system characteristics. The objectives are to determine whether the vaccine prevents COVID-19 disease, to see if the study…
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The purpose of this study is to assess the effect of sacubitril/valsartan vs. valsartan on changes in NT-proBNP, safety, and tolerability in HFpEF patients with a WHF event (HFpEF decompensation) who have been stabilized and initiated at the time of or within 30 days post-decompensation.
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Increasingly, over the last 15 years, antibiotic resistant infections in the Atlanta 20 county metropolitan area have continued to soar — this area represents a diverse racial/ethnic population. Project HIRaCAARI stands for Project Health Information Resources and Community-Associated Antibiotic Resistant Infections. The goal of Project HIRaCAARI is to reduce health disparities among people of color…
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The purpose of this study is to characterize the distribution of lipoprotein(a) (Lp(a)) levels among participants with a history of ASCVD as defined by their medical history.
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ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants to enable the monitoring of possible delayed effects of aspirin treatment, primarily on cancer incidence, metastases and mortality.
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Goal is to identify solutions to lower the effects of serious illness in pregnancy and/or after delivery which can sometimes lead to death and to advocate for changes in laws and programs to prevent future maternal deaths and severe illness.
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The Morehouse School of Medicine Prevention Research Center conducted a Community Health needs and Assets Assessment. As a neighborhood resident of Neighborhood Planning, your opinion about the health concerns and resources in your community is important to us. The information we received from the survey help us develop health programs and improve prevention education services…
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A prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
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